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Bio-Fires – An Eco-Friendly Alternative to Real Fires Biofires are a warm and cosy method of heating your home without releasing harmful gases or soot. They are easy to set up as an electrical fire. The BARDA-funded contract supports development of the BioFire Emerging CoV Panel, a nucleic acid amplification test for use with BioFire FilmArray Systems to identify human coronaviruses that are emerging and known in nasopharyngeal and oropharyngeal sw and saliva samples. Eco-friendly Bioethanol is an eco-friendly alternative to wood or gas. The fuel is created using plant by-products, and the natural process converts sugars into alcohol. It is a better option than other fireplaces since it does not emit harmful emissions, and has less carbon footprint. Bioethanol is a safer alternative to other fires as it doesn't emit smoke or soot. It does not require a flue, and can be used in the garden or home. Multi-drug resistant bacteria (MDR) are one of today's most serious health threats. New methods of testing can identify MDR bacteria early and prevent further complications. One such test is the BioFire FilmArray multiplex PCR system. This test employs a symptom-driven approach to detect the most frequent pathogens that cause sepsis. The results are available within an hour so that providers can begin treatment immediately. Molecular PCR is a process that amplifies DNA or RNA molecules into millions or billions of copies. This makes it possible to test small amounts of body fluids or tissues to determine the presence of specific genetic sequences. It is a useful instrument for lab professionals, and it can assist them in diagnosing serious illnesses in a timely and cost-effective manner. The BioFire FilmArray PCR system is an innovative tool for the diagnosis of infectious diseases, and it can be utilized to perform a variety of applications in hospitals and labs. For respiratory tests, a simple swab can be applied to your nose and sent to the lab to be analyzed. BioFire's system offers a quick turnaround time and allows clinicians to respond quickly. This means less time waiting for results and better patient outcomes. The Chanouf Farm-Biofire company developed an Agroforestry waste recycling system, which utilizes pear and olive tree waste to make organic charcoal and biomass energy. The products are sold to the public to replace traditional wood charcoal and coal briquettes with eco-friendly alternatives. bio ethanol fires -waste products are suitable for burning in a Kachelofen fireplace which generates radiant heat and is a more sustainable alternative to gas or electric fires. Clean burning When you use a bio fire you aren't only saving energy, but you're also helping the environment by using a renewable fuel source. The combustion of bioethanol does not produce harmful gases such as carbon dioxide. Instead, it releases only heat and water vapour. This makes it a cleaner and safer alternative for indoor use. Ethanol can be made through the fermentation of sugars from plants. It is an energy source that is renewable. It can be produced quickly, and it will not be depleted like fossil fuels like coal and oil. Bioethanol helps reduce the dependency on imports from foreign countries and reduces the risks that come with supply shortages. Bio-fires are very easy to install and can be used in existing fireplace openings or as freestanding units. This makes them an alternative to wood and gas fires. They're also an excellent choice for offices and homes that do not have chimneys or flues. When a bio-fire is ignited the burner is equipped with a special media that absorbs ethanol fuel liquid and makes it accessible for combustion. The ethanol fuel is ignited in the flames, and the vapors are released into the atmosphere via the vent. The flames appear more natural and gives a mesmerising beauty that can't be replicated with wood or gas fires. Bio-fires have the advantage of not needing a vent or flue to replenish oxygen during combustion. They also don't create the carbon monoxide that must be vented out into the room in gas fires that are open-fronted. The BioFire Respiratory Panel utilizes multiplex PCR technology to simultaneously test for 19 respiratory pathogens in about an hour. This enables doctors to identify and eliminate respiratory diseases quicker than they could by using standard laboratory tests that require patients visits. Both the patient and the health system benefit from this. Safe indoors Bio-fires can be used indoors much more safely than traditional fires since they don't release smoke, ash, or carcinogenic fumes. They also don't release carbon monoxide that can cause death if breathed in. The bio-ethanol fuel that they use is flammable however it is important to be extremely careful when handling the burner and refilling your fire. The fuel should only be added after the burner has been switched off and your fire has been cooled. Any spills need to be cleaned immediately. The company's diagnostic FilmArray system – BioFire Torch and BioFire 2.0—are simple to use and can run eight different diagnostic panels that have been cleared by the US Food and Drug Administration as well as three additional panels approved for use in emergencies, and six environmental test panels. The tests include a respiratory panel that was developed to quickly detect and differentiate respiratory illnesses such as COVID-19. emerging coronaviruses and COVID-19. The Biomedical Advance Research and Development Initiative, which is part of the US Department of Defense Strategic Access Program has awarded the COVID-19 panel with a grant. The COVID-19 test is an antigen-based system, allowing clinicians to distinguish the symptoms caused by COVID-19 and other respiratory infections with the same precision as the rapid antigen tests currently being used. In addition, the company is developing a SARS-CoV-2 assay for its Respiratory 2.1 Panel. This multiplexed nucleic acids amplification test will be available on the BioFire filmArray 2.0 and Torch Systems and will detect SARS CoV-2 and 21 respiratory pathogens in saliva and nasopharyngeal samples within less than an hours. The assay is being developed on an rapid timeframe, and submission to the FDA for EUA and 510(k) clearance is expected in the third quarter of 2020. Although bio-ethanol flame-effect fires are extremely safe to use, they should be kept away from combustible materials like blankets, curtains and cushions. It is not recommended to place them near anything that can catch fire. Keep all flammable items away from the flame-effect fires by at least 10 feet. The bioethanol fuel should be stored in a dry, secure space that is not easily reached by pets or children. Simple to use A bioethanol fireplace is easy to use and has no flue to be concerned about. All you need is a location to place it in and some fuel. After you've filled the burner and lit it, ignite it. This will produce the appearance of a fire that is like the real flame. When the flame is lit, it will heat the room without releasing much smoke. It also produces heat, similar to a wood-burning fireplace. Bio fires are easy to maintain and don't require any servicing or maintenance, other than the occasional wipe down. The BioFire RP2.1 Easy test unlike other tests that use an syndromic approach to detect typical signs of infection it can give results in 45 minutes. The test is specifically designed for patients with upper respiratory symptoms and has a 98% specificity rate. The test can detect up to 19 bacteria and viruses in a single sample, making it a great option for the treatment of patients. The BioFire platform combines multiplex testing, sample preparation, and result reporting in one integrated platform. This allows laboratories to streamline their workflow and eliminates the need for a sequential approach that involves individual and send-out test. This can result in better patient outcomes, as the right test is used first time, and the need for expensive tests based on culture is eliminated. In addition, the BioFire system can identify pathogens and their antimicrobial resistance genes at the molecular level, giving data that is more precise than traditional methods. Molecular diagnostics are increasingly being used to improve the care of patients and outcomes. The BioFire RP2.1 plus panel makes use of a syndromic approach to simultaneously target 23 of the most frequently involved pathogens in respiratory infections. The test can be run on the BioFire FilmArray 2.0 and Torch systems and results are available in approximately 45 minutes. In the US this test is available currently under FDA Emergency Use Authorization (EUA), and will be commercially available after the initial DoD demand is satisfied. The BioFire Defense team has also developed a fully automated sample-to result assay for rapid identification of COVID-19. The test is in the process of development and will be available once initial DoD demand is fulfilled.